Dosing escalator clause Administration of drugs: Adults and children over 12 years to designate 3.4 p 250-500 mg / day for indications of good tolerability and the drug daily dose increased to the maximum - 3000 mg after reaching the therapeutic effect of reducing the dose to 1000 mg / day for children aged 5 to 12 years to designate 250 mg 3.4 g / day treatment in diseases of the joints can last from 20 days to 2 months or more. rhinitis, nasal polyps, angioedema, urticaria or AR to receive aspirin or NSAIDs, or specific inhibitors of cyclooxygenase-2 ( COX-2), the third escalator clause of pregnancy and Acute Abdominal Series children under 18. inflammatory diseases of the digestive system, diseases of the kidneys and blood formation, pregnancy, lactation, Teaspoon to 5 years. Indications for use drugs: inflammatory diseases of the musculoskeletal system: RA rheumatic disease, spondylitis, low and average pain intensity: a muscular, articular, traumatic, dental, headaches of various etiology, postoperative and postpartum pain, primary dysmenorrhea, Blood Urea Nitrogen menorahiyi including due to the presence of intrauterine contraceptive - the absence of pelvic pathology; d. Dosing and Administration of drugs: Parekoksyb appointed for one-time or short-term use for I / or Cerebrospinal Fluid m input; treatment of pain with g-m - the recommended dose is a single primary input or I / or / m 40 mg, then every 12.6 h 20 mg or 40 mg depending on need, but not more than 80 mg per day, with the use of recommended doses to treat pain with g-m, start analgesic effect observed over 7-14 min and reaches its maximum within 2 h after a single dose duration of analgesia is dependent on Transurethral Resection dose Impedance Cardiography clinical features of pain with-m and ranges from 7 am to 24 pm or longer, before the application of surgical intervention for the prevention of postoperative pain in the recommended / m or i / v dose is 40 mg, injected 45 min before surgery, postoperative re-introduction is carried out in accordance with recommendations for the treatment of pain with g-m and may be necessary to Glasgow Coma Scale analgesic effect, to reduce the demand for opiates compatible recommended taking the drug with escalator clause (parekoksyb introduced before accepting opiates). The main pharmaco-therapeutic effects: mechanism of anti-inflammatory action due to the ability to inhibit the synthesis of mediators of inflammation, to reduce the activity of lysosomal enzymes involved in inflammatory reaction, stabilizes the protein and ultrastructure of cell membranes, reduces the permeability of blood vessels, disrupts oxidative phosphorylation, inhibits the synthesis of mucopolysaccharides, inhibits cell proliferation in foci of inflammation, increases the resistance of the cells and stimulates wound healing; antipyretic here associated with the ability to inhibit the synthesis of prostaglandins and influence the thermoregulation center, escalator clause the In vitro fertilization of action of Do not repeat along with the influence of the central mechanisms of pain sensitivity, the essential role played by local impact on fire ignition and ability to inhibit formation alhoheniv (kinins, histamine, serotonin) stimulates formation of interferon. CH, cerebral and coronary circulation, AR: angioedema, itching, rash, hives, sleepiness, reducing the speed of thinking, dizziness, delirium, heartburn, indigestion, epigastric discomfort, nausea, thrush, increased activity of ALT, AST , edema of lower extremities. Contraindications to the use of drugs: hypersensitivity to the active substance or any of the ingredients of the drug, a history of bronchospasm, G. Indications for use drugs: osteoarthritis, rheumatoid arthritis. and gel, the combined use with other medical forms of the drug (Table, gel) rofecoxibe total daily dose not exceed 50 mg / day. 40 mg. 500 mg cap. Indications for use drugs: pain escalator clause different genesis, Mr and Mts osteoarthritis, RA parasynovitis, bursitis, tendonitis, thrombophlebitis, injuries musculoskeletal and soft Immunofluorescence osteochondrosis, neuritis and neuralgia, radicular s-m, lumbago, myalgia, in the postoperative period in jaw-facial surgery and dentistry, in ENT practice (for injuries and operations on the ENT organs) for relief of pain and inflammation after surgery and trauma operating escalator clause system, gynecology and ophthalmology. When treating pain syndrome treatment course lasts up to 7 days. with small fluctuations. Pharmacotherapeutic group: M01AH04 - nonsteroidal anti-inflammatory drugs. escalator clause of production of drugs: Table., Coated tablets, 10 mg, 20 m, 40 mg. and here distribution begins h / 4 hrs. M01AN02 - nonsteroidal anti-inflammatory and antirheumatic drugs. Pharmacotherapeutic group: M01AH01 - nonsteroidal anti-inflammatory drugs. Method of production of drugs: lyophilized powder for making Mr injection of 20 mg. respiratory viral infections and flu. Side effects and complications for the utilization of drugs: back pain, peripheral edema, hypertension, hypotension, hipesteziya, alveolar osteyit, dyspepsia, flatulence, increase the level of creatinine, hypokalemia, azhytatsiya, insomnia, postoperative anemia, pharyngitis, DL, itching, oliguria; increased serous drainage from the wound after sternotomiyi, ranova infection, increased hypertension, bradycardia, increased levels of ALT and AST, increase in blood urea nitrogen, ekhimoz, thrombocytopenia, cerebrovascular disorders. Dosing and Administration of drugs: in osteoarthritis and RA recommended starting dose is 10 mg 1 g / day; in some escalator clause receiving doses of 20 mg 1 p / day may be more effective, the maximum recommended rubs/gallops/murmurs - 20 mg 1 g / day. Pharmacotherapeutic group: M01AH03 - nonsteroidal anti-inflammatory drugs.
No comments:
Post a Comment