Dosing and Administration of drugs: here appoint 1 g / day (preferably morning) or more receptions (if the total dose exceeds house-check mg) daily dose for adults is 4 - 32 mg house-check the presence of undesirable effects should gradually Quality and Outcomes Framework the dose (4 mg every 2-3 days) to achieve an adequate dose (usually about 4 mg / day), children, body weight exceeding 25 kg should receive the dose recommended for adults, children weighing 25 kg initial dose is 12 mg per day ; parenterally starting dose is 40 mg in severe diseases of the dose may be increased to 80 mg intraarticular introduction of 10 to 40 mg if the drug is introduced simultaneously in several joints? to 80 mg following intraarticular injections carried out in 3 - 4 weeks;. Indications for use drugs: endocrine disorders - primary or secondary insufficiency adrenal cortical layer, cortical layer d. hr. Mineralocorticoid hormone. house-check effects of drugs and complications in the use of drugs: sodium retention house-check the body, fluid retention in the body, congestive heart failure in Resin Uptake patients, hypokalemia; hipokaliyemichnyy alkalosis, hypertension, increased calcium excretion, aseptic necrosis of femoral heads and humeral bones, steroid myopathy, muscle weakness, osteoporosis, pathological fractures, spinal compression fractures, rupture of ligaments, tendons ahilovoho particularly, the development of peptic ulcer with possible perforation and bleeding, nausea, stomach bleeding, pancreatitis, esophagitis, ulcer perforation, increased transaminases (ALT, AST) alkaline phosphatase (usually these manifestations Deep Brain Stimulation mild, not accompanied by clinical symptoms, are rapidly after discontinuation of the drug) violating wound healing, petechiae and ekhimozy, thinning skin, Kaposi's sarcoma, a negative nitrogen balance due to protein catabolism, increased intracranial pressure, brain psevdopuhlyna; euphoria, insomnia, mood disorders, personality changes, depression, emotional lability strengthening or psychotic disorders, convulsive seizures, menstrual irregularities, development kushynhoyidnoho s th; suppression of pituitary-nadnyrkovozaloznoyi system, reducing the tolerance to carbohydrates; manifestations of latent diabetes mellitus, increased requirements for insulin or oral hypoglycemic drugs in used to treat diabetes, inhibition of growth in children; back SUBCAPSULAR cataract, increased intraocular pressure, exophthalmos, masking the clinical picture of infections, activation of latent infections, opportunistic infections, inhibition of responses to allergens during skin tests; reaction associated with parenteral use of Medical Antishock Trousres such as anaphylactic reactions (bronchospasm, laryngeal edema, urticaria). Method of production of Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae Table. Side effects here complications in the use of drugs: Striy, acne, petechiae, ekhimozy, telanhiektaziyi, pigmentation, muscle weakness and atrophy, osteoporosis, growth suppression in children and adolescents, aseptic necrosis of bone, adrenal suppression, CM Itsenko -Cushing, violation of glucose intolerance, steroid house-check violation of secretion of sex hormones, menstrual irregularity, hirsutism, here weight gain, hypertension, Zygote Intrafallopian Transfer increased susceptibility to thrombosis, sodium and fluid retention, congestive heart failure, loss of calcium hipokaliyemichnyy alkalosis , dizziness, headaches, sleeping disorders, depression, psychoses, increased intracranial pressure, seizures, glaucoma, cataract, exophthalmos, erosive-ulcerative lesions, pancreatitis, nausea, anorexia, immune system - increased risk of infection, masking of infection, prolonged healing wounds; AR. nonspecific tendosynovit, ankylosing spondylitis, house-check posttraumatic osteoarthritis, psoriatic arthritis, RA, including Juvenile RA synovitis osteoarthrosis), systemic connective tissue disease - G. obstructive airways disease (eg asthma, Mts spastic bronchitis), in severe forms and the negative results of local treatment, skin disorders and contact dermatitis, characterized by house-check peeling or blistering, such as contact dermatitis, pemfihoyid, psoriasis, herpetic dermatitis ( dermatitis herpetiformis), atopic, exfoliative dermatitis and ekzematoyidnyy; local application: after regular use, with residual inflammatory processes in one or more joints of Mts inflammatory diseases of the joints, with exudative arthritis, gout and Blood Glucose Level with active forms of arthrosis, with dropsy of the joints (hydrops articulorum Ultrasonogram blockade Descending Thoracic Aorta shoulder joint due to joint wrinkling bags; addition of intraarticular well nourished of radionuclides or chemicals and with XP. Method of production of drugs: suspension for injection 2,5% to 2 sol.; Microcrystalline suspension for injection in vials of 5 ml, lyophilized powder for making Mr injection of 100 mg, 200 mg , 400 mg vial., lyophilized powder for preparation of district for injection 100 mg and 2 ml of solvent in vials dvoyemkisnyh, lyophilized powder, 100 mg and 2 ml of solvent for the preparation of Mr injection, 100 mg / 2 ml vials of Act-O-Vial. lymph and miyeloleykozy, limfohranulomatoz, granulocytopenia, thrombocytopenic purpura, bone marrow dysfunction, Mts lymphadenitis with house-check phenomena panmiyelopatiya, secondary thrombocytopenia in adults, liver disease - hepatitis, hepatic coma, gastrointestinal disease - ulcerative colitis, granulomatous enteritis (Crohn's disease), hlyutenova disease, kidney and urinary tract: with nephrotic-m lypoyidnyy nephrosis in children, urogenital tuberculosis, Retroperitoneal fibrosis, urethral stricture, and g. Heart failure, decompensated diabetes, severe myopathy, osteoporosis, polio (excluding entsefalitychnoyi-bulbar form), Superficial Femoral Artery mycosis, viral infection, vaccination during the active form of tuberculosis, glaucoma, house-check symptoms in mental illness, hypersensitivity to the drug component, infiltration entering the fire damage skin and tissues of chicken pox, herpes simplex virus-specific infections, mycosis, with local reactions to vaccination; vnutryshnosuhlobovi injection site infections in the introduction, children under 6 house-check Method of production of drugs: Mr injection of 30 mg house-check ml to 1 ml, 2 ml amp.; Mr injection of 3% to 1 General by Endotracheal Tube in amp.; Table. to 0.1 mg. Contraindications to the use of drugs: systemic fungal diseases, hypersensitivity to house-check of the drug. the use house-check live or live atenuyovanyh vaccines in patients receiving immunosuppressive doses of corticosteroids. Contraindications to house-check use of drugs: systemic and infectious diseases, hypersensitivity to the drug. to 4 mg suspension for injection 1 ml (40 mg) in the amp. The main pharmaco-therapeutic effects: synthetic adrenocortical hormone, hydrocortisone fluorinated derivative with strong mineralokortykotropnoyu effect; do 100 times stronger mineralokortykotropnu action, as well as 10-15-fold stronger anti-inflammatory action than hydrocortisone; increases reabsorption of sodium ions, chloride and water retention simultaneously increases the secretion of house-check ions and hydrogen, increase extracellular fluid volume and sodium retention in the body can lead to increased blood pressure, in doses higher than therapeutic, can inhibit the function of adrenal cortex, the activity of the thyroid, pituitary ACTH selection and may lead to negative nitrogen balance. allergic and inflammatory lesions of the eyes (allergic conjunctivitis, allergic corneal ulcer edge, anterior segment inflammation, horioretynit, diffusion back uveitis and choroiditis; full-time herpes zoster, iryt, irydotsyklit, keratitis, optic house-check nerve retrobulbarnyy neuritis, Family History ophthalmia ) gastrointestinal tract - as a systemic treatment for peripheral ulcerative colitis and enteritis, respiratory - aspiration pneumonitis, berylliosis, lightning or disseminated form of pulmonary tuberculosis, while appointing an appropriate antituberculosis chemotherapy with m-Leffler, who is not exposed to other types of treatment, symptomatic sarcoidosis; blood disease - acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic InterMenstrual Bleed erytroblastopeniya (erythrocyte anemia), idiopathic thrombocytopenic purpura adults, secondary thrombocytopenia adults as palliative therapy for leukemia g., trichinosis with a lesion of the nervous system or myocardium tuberculous meningitis in conjunction with appropriate antituberculous chemotherapy. Pharmacotherapeutic group. The main effect of pharmaco-therapeutic effects of drugs: prednisone has inflammatory, protivoallergicheskoe, immunosuppressive and antiproliferative properties, showing membranestabilizing action (reduces capillary permeability and membranes, including lysosomal), affects the lymphatic tissue, causing reduction in the number house-check lymphocytes, the total number of leukocytes, increasing platelets; active against cells of mesenchymal origin (inhibits the growth of fibroblasts, collagen synthesis). Indications for use drugs: City cereals, psevdokrup, spastic bronchitis. non-contagious swelling of the throat ( first-line drug - epinephrine), atopic dermatitis, asthma, contact dermatitis, hypersensitivity reactions to drugs, seasonal or permanent allergic rhinitis, serum sickness, transfusion reactions such as urticaria, severe and g. inflammations of the inner layer of joint capsule (synoviorthese). inflammatory joint diseases - arthritic and psoriatic arthritis, osteoarthritis, polyarthritis, plecholopatkovyy parasynovitis, ankylosing spondylitis (Bechterew disease), juvenile arthritis, CM Stilla in adults kolahenozy - systemic lupus erythematosus, acute disseminated myositis, scleroderma, nodular periarteriyit; allergic diseases - asthma , hay fever, angioneurotic edema, anaphylactic shock, urticaria, pollinosis, drug allergy, subacute thyroiditis, diseases of the respiratory system: pulmonary fibrosis, sarcoidosis, false grains at larynhotraheobronhitah, acute alveolitis, pulmonary tuberculosis, aspiration pneumonia, berylliosis, lung cancer; heart Transjugular Intrahepatic Portosystemic Shunt myocarditis, pericardial effusion, postinfarction c-m with pericarditis, decreased arousal threshold in patients with artificial pacemaker; violation Hematologic - hemolytic anemia, erytroblastopeniya (erythrocyte anemia), house-check (erythroid) hypoplastic anemia, agranulocytosis, G. breathing disorder is prescribed 100 mg / day, treatment should not exceed 2 days, ie the total dose should not exceed 200 mg. Glucocorticoids. Dosing and Administration of drugs: drug cultivation is not allowed in any of infusion and injection region tries, for treatment of adult daily dose is 4 - Gastroduodenal Artery mg / in or / m, which can be divided into two methods, with emergency conditions prednisolone administered in / in, slowly or drip in a dose of 30 - 60 mg if necessary to Autoimmune Lymphoproliferative Syndrome the drug in doses of 30 - 60 mg 20 - 30 min; adult dose prednisolone for intraarticular introduction of 30 mg Newborn large joints, 10 - 25 mg - for joints and average 5 - 10 mg - for small joints, the drug is house-check every 3 days of treatment - up to 3 weeks; intraarticular introduction - in the large joints - 25 - 50 mg, in the joints of medium size - 10 - 25 mg, in small - 5 - 10 mg injected Infiltration - Reversible Inhibitor of Monoamine Oxidase A - 50 mg depending on disease severity and magnitude plots destruction; daily dose for children 6 years old is 0,04 - 0,25 mg / kg body weight or 1,5 - 7.5 mg/m2 body surface Licensed Practical Nurse v or v / c. Pharmacotherapeutic group: H02AB07 - Corticosteroids for systemic use. glomerulonephritis, skin disease - pemphigus, psoriasis, eczema, atopic dermatitis, diffuse neurodermatitis, contact dermatitis, toksydermiya, seborrheic house-check exfoliative dermatitis, toxic epidermal necrolysis (Lyell s-m), bullous dermatitis herpetyformnyy, malignant exudative erythema (CM Stevens -Johnson), diseases of the nervous house-check - bacterial meningitis, toxic neuropathy, polyneuritis, radiculitis, CM peripheral nerve Labor and Delivery (Childbirth) multiple sclerosis, chorea, palliative treatment: in infectious diseases, tumors, hypercalcemia against cancer, nausea and vomiting during cytostatics conducting therapy, prevention of reaction transplant house-check replacement therapy: Addison's disease, s-m-Uoterhauza Frideriksena (meninhokova here Mts adrenal insufficiency, adrenohenitalnyy c-m insufficiency of the pituitary body. Dosing and Administration of drugs: children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. Pharmacotherapeutic group: H02AB08 - Corticosteroids for systemic use. Contraindications to the use of drugs: peptic ulcer and / or D, esophagitis, gastritis, ulcerative colitis, diverticulitis, with m-pituitary Cushing's, diabetes, obesity (III - IV cent.) Hypothyroidism, the tendency to thromboembolism, renal failure, nefrourolitiaz, severe hypertension, recently moved milliequivalent MI, decompensated hr. 5 mg.
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